Cortivazol

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Cortivazol
Cortivazol.png
Systematic (IUPAC) name
(11β,16α)-21-(Acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
?
Identifiers
CAS number 1110-40-3 YesY
ATC code H02AB17
PubChem CID 66249
ChemSpider 59633 YesY
UNII YM183K0H63 YesY
KEGG D03594 YesY
ChEMBL CHEMBL2105842 N
Chemical data
Formula C32H38N2O5 
Molecular mass 530.655
 N (what is this?)  (verify)

Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.[1]

It is sometimes abbreviated "CVZ".[2]

References[edit]

  1. ^ Schlechte JA, Simons SS, Lewis DA, Thompson EB (October 1985). "[3H]cortivazol: a unique high affinity ligand for the glucocorticoid receptor". Endocrinology 117 (4): 1355–62. doi:10.1210/endo-117-4-1355. PMID 4029081. 
  2. ^ Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H (May 2005). "The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor". Mol. Endocrinol. 19 (5): 1110–24. doi:10.1210/me.2004-0264. PMID 15677712. 

External links[edit]

Cortivazol at the US National Library of Medicine Medical Subject Headings (MeSH)