Cortivazol

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Cortivazol
Cortivazol.png
Systematic (IUPAC) name
(11β,16α)-21-(Acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
?
Identifiers
CAS number 1110-40-3
ATC code H02AB17
PubChem CID 66249
ChemSpider 59633 YesY
UNII YM183K0H63 YesY
KEGG D03594 YesY
ChEMBL CHEMBL2105842
Chemical data
Formula C32H38N2O5 
Mol. mass 530.655
 YesY (what is this?)  (verify)

Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.[1]

It is sometimes abbreviated "CVZ".[2]

References[edit]

  1. ^ Schlechte JA, Simons SS, Lewis DA, Thompson EB (October 1985). "[3H]cortivazol: a unique high affinity ligand for the glucocorticoid receptor". Endocrinology 117 (4): 1355–62. doi:10.1210/endo-117-4-1355. PMID 4029081. 
  2. ^ Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H (May 2005). "The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor". Mol. Endocrinol. 19 (5): 1110–24. doi:10.1210/me.2004-0264. PMID 15677712. 

External links[edit]

Cortivazol at the US National Library of Medicine Medical Subject Headings (MeSH)