Counterimmunoelectrophoresis

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Plasmodium Glutamate dehydrogenase (pGluDH) separated by counterimmunoelectrophoresis[1]

A laboratory technique used to evaluate the binding of an antibody to its antigen. Counterimmunoelectrophoresis is similar to immunodiffusion, but with the addition of an applied electrical field across the diffusion medium, usually an agar or polyacrylamide gel. The effect is rapid migration of the antibody and antigen out of their respective wells towards one another to form a line of precipitation, or a precipitin line, indicating binding.[2]

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References[edit]

  1. ^ Ling IT., Cooksley S., Bates PA., Hempelmann E., Wilson RJM. (1986). "Antibodies to the glutamate dehydrogenase of Plasmodium falciparum". Parasitology 92 (2): 313–324. doi:10.1017/S0031182000064088. PMID 3086819. 
  2. ^ http://medical-dictionary.thefreedictionary.com/counter+immunoelectrophoresis
  • Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. Chp 15 Principles of Laboratory Diagnosis. ISBN 0-8385-8529-9. 

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