Developed by SanDisk, the Cruzer Enterprise is an encrypted USB flash drive. This secure USB drive imposes a mandatory access control on all files, storing them in a hardware-encrypted, password-protected partition. The Cruzer Enterprise is designed to protect information on company-issued USB flash drives.
The Cruzer Enterprise is compatible with Central Management and Control (CMC) server software. The CMC centrally manages the drive, enabling password administration, data backup, and termination if the drive is lost or stolen. The Cruzer Enterprise currently supports Microsoft Windows 2000 SP4, Windows XP SP1, Windows Server 2003, Windows Vista, and Apple OS X 10.4 and 10.5.
SanDisk announced the end-of-life for the Cruzer Enterprise product line in November 2010. 
Prior to the end-of-life announcement, the SanDisk Cruzer Enterprise competed with various other secure USB drives, including IronKey, Kingston, Verbatim and also disk encryption software such as FreeOTFE and TrueCrypt.
- Garretson, Cara (Jun 5, 2007). "USB Flash Drives Come with Built-in Security". PCWorld. Retrieved August 19, 2009.
- "Cruzer Enterprise Release Notes" (PDF). SanDisk. May, 2007. Retrieved August 19, 2009.
- Gonsalves, Antone (December 5, 2008). "SanDisk Offers Secure USB Flash Drive For Mac". InformationWeek. Retrieved August 19, 2009.
- "Cruzer Enterprise End of Life Announcement" (PDF). SanDisk. November, 2010. Retrieved April 14, 2013.
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