Intestinal crypt

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Intestinal crypt
Micrograph of the small intestine mucosa showing the crypts of Lieberkühn - bottom 1/3 of image. H&E stain.
Latin	glandulae intestinales
Gray's	subject #248 1174

In histology, an intestinal crypt, also crypt of Lieberkühn and intestinal gland, is a gland found in the epithelial lining of the small intestine and colon.

The crypts secrete various enzymes, including sucrase and maltase, along with endopeptidases and exopeptidases. Also new epithelium is formed here, keeping in mind that the epithelium at this site is frequently worn away by the passing food. Loss of proliferation control in the crypts is thought to lead to colorectal cancer.

The basal portion of the Crypt contains multipotent stem cells. At each mitosis one daughter remains a stem cell while the other differentiates and migrates up the side of the crypt and eventually the villus. Goblet cells are among the cells produced in this fashion.

Contents 1 Eponym 2 See also 3 Additional images 4 External links

[edit] Eponym

The eponymous term (crypts of Lieberkühn) is named after the 18th-century German anatomist Johann Nathanael Lieberkühn.

[edit] See also

• Cryptitis

[edit] Additional images

different stages of Coeliac Disease

General structure of the gut wall.

An intestinal gland from the human intestine.

[edit] External links

• Illustration at trinity.edu
• Illustration at kumc.edu
• Illustration at uokhsc.edu
• synd/2651 at Who Named It?
• intestinal+glands at eMedicine Dictionary

v • d • e Anatomy of torso, digestive system: Gastrointestinal tract, excluding mouth (TA A05.3-7, GA 11.1141) Upper GI Hypo- pharynx Piriform sinus spaces: Peripharyngeal space (Retropharyngeal space, Parapharyngeal space) · Retrovisceral space (Retropharyngeal space, Danger space) · Prevertebral space Pterygomandibular raphe · Pharyngeal raphe · Buccopharyngeal fascia · Pharyngobasilar fascia Pharyngeal muscles Esophagus UES, LES Stomach Gastric rugae · gastric pits · cardia/gland · fundus/gland · pylorus/gland · pyloric antrum · pyloric canal · greater curvature · lesser curvature · angular incisure Lower GI Intestine: small Duodenum (Suspensory muscle, Major duodenal papilla, Minor duodenal papilla, Duodenal cap) • Duodenojejunal flexure • Jejunum • Ileum (Terminal ileum) • Ileocecal valve continuous (intestinal villus, crypts of Lieberkühn, circular folds) Intestine: large Vermiform appendix • Cecum • Colon (ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon) continuous (taenia coli, haustra, epiploic appendix) Termination Rectum: Houston valve • rectal ampulla • pectinate line Anal canal: anal valves • anal sinuses • anal columns • Hilton's white line Anus: Sphincter ani internus muscle • Sphincter ani externus muscle Lymph GALT: Peyer's patches (M cells) digestive system navs: anat of tract,glands,perit,diaphragm/physio/dev, noncongen/congen/congen of d+w/neoplasia, symptoms+signs/eponymous, proc

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