The airport has not had service from a major airline since US Airways Express carrier Air Midwest left in September 2001. But from 2001 the airport was served by a spin-off of the former Pan Am Airways group until May 2003.
On the second level of the airport terminal is the Cohongaronta Gallery (Cohongaronta being a Shawnee name for the Potomac River) with an array of displays on the history of the Potomac Highlands area. The centerpiece of the gallery is a 40% scale replica of the Wright Brothers 1903 Wright Flyer. A 70-foot-long (21 m) time line highlights dates and events for the Potomac Highlands region. The gallery is open to the public during terminal business hours.
Greater Cumberland Regional Airport covers 314 acres (127 ha) and has two asphaltrunways: 5/23, 5,048 x 150 ft (1,539 x 46 m) and 11/29, 2,442 x 150 ft (744 x 46 m).
In the year ending August 2, 2006 the airport had 14,300 aircraft operations, an average of 39 per day: 98% general aviation and 2% military. 69 aircraft are based at this airport: 81% single engine, 7% gliders, 6% multi-engine, 3% jet aircraft and 3% helicopters.