Cuscohygrine

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Cuscohygrine
Chemical structure of cuscohygrine
Cuscohygrine ball-and-stick.png
Names
IUPAC name
1,3-Bis-(1-methylpyrrolidin-2-yl)-propan-2-one
Identifiers
454-14-8
ChemSpider 389876
Jmol-3D images Image
KEGG C06521
Properties
C13H24N2O
Molar mass 224.34 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Cuscohygrine is a pyrrolidine alkaloid found in coca. It can also be extracted from plants of the family Solanaceae as well, including Atropa belladonna (deadly nightshade), Datura inoxia and Datura stramonium (jimson weed). Cuscohygrine usually comes with other, more potent alkaloids like atropine or cocaine.

Cuscohygrine (along with the related metabolite hygrine) was first isolated by Carl Liebermann in 1889 as an alkaloid accompanying cocaine in coca leaves (also known as Cusco-leaves).

Cuscohygrine is an oil that can be distilled without decomposition only in vacuum. It is soluble in water. It also forms a crystalline trihydrate, which melts at 40–41 °C.

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