Cyanoalanine nitrilase

cyanoalanine nitrilase
Identifiers
EC number	3.5.5.4
CAS number	85638-44-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a cyanoalanine nitrilase (EC 3.5.5.4) is an enzyme that catalyzes the chemical reaction

3-cyano-L-alanine + 2 H₂O $\rightleftharpoons$ L-aspartate + NH₃

Thus, the two substrates of this enzyme are 3-cyano-L-alanine and H₂O, whereas its two products are L-aspartate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is 3-cyano-L-alanine aminohydrolase. This enzyme is also called beta-cyanoalanine nitrilase. This enzyme participates in cyanoamino acid metabolism.

References

• Yanase H, Sakai T and Tonomuro K (1983). "Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13". Agric. Biol. Chem. 47 (3): 473–482. doi:10.1271/bbb1961.47.473.