Cystine reductase

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cystine reductase
Identifiers
EC number 1.8.1.6
CAS number 9029-18-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a cystine reductase (EC 1.8.1.6) is an enzyme that catalyzes the chemical reaction

2 L-cysteine + NAD+ \rightleftharpoons L-cystine + NADH + H+

Thus, the two substrates of this enzyme are L-cysteine and NAD+, whereas its 3 products are L-cystine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-cysteine:NAD+ oxidoreductase. Other names in common use include cystine reductase (NADH), NADH-dependent cystine reductase, cystine reductase (NADH2), and NADH2:L-cystine oxidoreductase. This enzyme participates in cysteine metabolism.

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