Molecular formula C
9H 13N 3O 5
Molar mass 243.22 g mol
Except where noted otherwise, data are given for materials in their
standard state (at 25 °C (77 °F), 100 kPa)
(verify) (what is: / ?)
Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N 1- glycosidic bond. Cytidine is a component of RNA.
cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine.
Dietary sources of cytidine [ edit ]
Dietary sources of cytidine include foods with high RNA (ribonucleic acid) content,
such as organ meats, Brewer's yeast, as well as pyrimidine-rich foods such as beer. During digestion, RNA-rich foods are broken-down into ribosyl pyrimidines (cytidine and uridine), which are absorbed intact. [1 ] In humans, dietary cytidine is converted into uridine, [1 ] which is probably the compound behind cytidine's metabolic effects. [2 ]
Cytidine analogs [ edit ]
There are a variety of cytidine
analogs with potentially useful pharmacology. For example, KP-1461 is an anti-HIV agent that works as a viral mutagen, and [3 ] zebularine exists in and is being examined for chemotherapy. Low doses of E. coli azacitidine and its analog decitabine have shown results against cancer through epigenetic demethylation. [4 ]
References [ edit ]
External links [ edit ]