Cytidine
| Cytidine | |
|---|---|
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4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one |
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| Identifiers | |
| CAS number | 65-46-3 |
| PubChem | 6175 |
| ChemSpider | 5940 |
| UNII | 5CSZ8459RP |
| KEGG | D07769 |
| MeSH | Cytidine |
| ChEBI | CHEBI:17562 |
| ChEMBL | CHEMBL95606 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C9H13N3O5 |
| Molar mass | 243.22 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond. Cytidine is a component of RNA.
If cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine.
[edit] Dietary sources of cytidine
Dietary sources of cytidine include foods with high RNA (ribonucleic acid) content,[1] such as organ meats, Brewer's yeast, as well as pyrimidine-rich foods such as beer. During digestion, RNA-rich foods are broken-down into ribosyl pyrimidines (cytidine and uridine), which are absorbed intact.[1] In humans, dietary cytidine is converted into uridine, [2] which is probably the compound behind cytidine's metabolic effects.
[edit] References
- ^ a b Jonas DA, Elmadfa I, Engel KH, et al. (2001). "Safety considerations of DNA in food". Ann Nutr Metab. 45 (6): 235–54. doi:10.1159/000046734. PMID 11786646. http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=anm45235.
- ^ Wurtman RJ, Regan M, Ulus I, Yu L (Oct 2000). "Effect of oral CDP-choline on plasma choline and uridine levels in humans". Biochem Pharmacol. 60 (7): 989–92. doi:10.1016/S0006-2952(00)00436-6. PMID 10974208. http://linkinghub.elsevier.com/retrieve/pii/S0006-2952(00)00436-6.
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