DBF4

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DBF4 zinc finger
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols DBF4 ; ASK; CHIF; DBF4A; ZDBF1
External IDs OMIM604281 MGI1351328 HomoloGene40892 ChEMBL: 4483 GeneCards: DBF4 Gene
Orthologs
Species Human Mouse
Entrez 10926 27214
Ensembl ENSG00000006634 ENSMUSG00000002297
UniProt Q9UBU7 Q9QZ41
RefSeq (mRNA) NM_006716 NM_001190717
RefSeq (protein) NP_006707 NP_001177646
Location (UCSC) Chr 7:
87.51 – 87.54 Mb
Chr 5:
8.4 – 8.42 Mb
PubMed search [1] [2]

Protein DBF4 homolog A is a protein that is encoded by the DBF4 gene in humans.[1][2][3]


Interactions[edit]

DBF4 has been shown to interact with ORC2L,[4] MCM7,[4] Cell division cycle 7-related protein kinase,[4][5][6] MCM3[4] and ORC6L.[4]

References[edit]

  1. ^ Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H (Jul 1999). "A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells". Mol Cell Biol 19 (7): 5083–95. PMC 84351. PMID 10373557. 
  2. ^ Lepke M, Putter V, Staib C, Kneissl M, Berger C, Hoehn K, Nanda I, Schmid M, Grummt F (Nov 1999). "Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes". Mol Gen Genet 262 (2): 220–9. doi:10.1007/s004380051078. PMID 10517317. 
  3. ^ "Entrez Gene: DBF4 DBF4 homolog (S. cerevisiae)". 
  4. ^ a b c d e Kneissl, Margot; Pütter Vera; Szalay Aladar A; Grummt Friedrich (Mar 2003). "Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells". J. Mol. Biol. (England) 327 (1): 111–28. doi:10.1016/S0022-2836(03)00079-2. ISSN 0022-2836. PMID 12614612. 
  5. ^ Kumagai, H; Sato N; Yamada M; Mahony D; Seghezzi W; Lees E; Arai K; Masai H (Jul 1999). "A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells". Mol. Cell. Biol. (UNITED STATES) 19 (7): 5083–95. ISSN 0270-7306. PMC 84351. PMID 10373557. 
  6. ^ Jiang, W; McDonald D; Hope T J; Hunter T (Oct 1999). "Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication". EMBO J. (ENGLAND) 18 (20): 5703–13. doi:10.1093/emboj/18.20.5703. ISSN 0261-4189. PMC 1171637. PMID 10523313. 

Further reading[edit]