DCP1A

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DCP1 decapping enzyme homolog A (S. cerevisiae)
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols DCP1A ; HSA275986; Nbla00360; SMAD4IP1; SMIF
External IDs OMIM607010 MGI1923151 HomoloGene10178 GeneCards: DCP1A Gene
RNA expression pattern
PBB GE DCP1A 218508 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 55802 75901
Ensembl ENSG00000162290 ENSMUSG00000021962
UniProt Q9NPI6 Q91YD3
RefSeq (mRNA) NM_018403 NM_133761
RefSeq (protein) NP_060873 NP_598522
Location (UCSC) Chr 3:
53.3 – 53.36 Mb
Chr 14:
30.48 – 30.53 Mb
PubMed search [1] [2]

mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene.[1]

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.[1]

Interactions[edit]

DCP1A has been shown to interact with DCP2[2] and UPF1.[2]

References[edit]

Further reading[edit]