DDEF1

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ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Protein DDEF1 PDB 2da0.png
PDB rendering based on 2da0.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ASAP1 ; AMAP1; CENTB4; DDEF1; PAG2; PAP; ZG14P
External IDs OMIM605953 MGI1342335 HomoloGene7684 GeneCards: ASAP1 Gene
RNA expression pattern
PBB GE DDEF1 221039 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 50807 13196
Ensembl ENSG00000153317 ENSMUSG00000022377
UniProt Q9ULH1 Q9QWY8
RefSeq (mRNA) NM_001247996 NM_001276461
RefSeq (protein) NP_001234925 NP_001263390
Location (UCSC) Chr 8:
131.06 – 131.46 Mb
Chr 15:
64.09 – 64.38 Mb
PubMed search [1] [2]

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 is a protein that in humans is encoded by the ASAP1 gene.[1][2]


Interactions[edit]

DDEF1 has been shown to interact with Src.[3]

References[edit]

  1. ^ Brown MT, Andrade J, Radhakrishna H, Donaldson JG, Cooper JA, Randazzo PA (Dec 1998). "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src". Mol Cell Biol 18 (12): 7038–51. PMC 109286. PMID 9819391. 
  2. ^ "Entrez Gene: DDEF1 development and differentiation enhancing factor 1". 
  3. ^ Brown, M T; Andrade J; Radhakrishna H; Donaldson J G; Cooper J A; Randazzo P A (Dec 1998). "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src". Mol. Cell. Biol. (UNITED STATES) 18 (12): 7038–51. ISSN 0270-7306. PMC 109286. PMID 9819391. 

Further reading[edit]