DMDM hydantoin

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DMDM hydantoin
DMDM hydantoin.svg
Abbreviations DMDMH
CAS number 6440-58-0 YesY
PubChem 22947
ChemSpider 21482 YesY
EC number 229-222-8
Jmol-3D images Image 1
Molecular formula C7H12N2O4
Molar mass 188.18 g/mol
EU classification Irritant Xi
R-phrases R43
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

DMDM hydantoin is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. DMDM hydantoin is an organic compound belonging to a class of compounds known as hydantoins. It is used in the cosmetics industry and found in products like shampoos, hair conditioners, hair gels and skin care products.[1][2]

DMDM hydantoin works as a preservative because the released formaldehyde makes the environment less favorable to the microorganisms.


A patch test study found "An increase in the use of DMDM hydantoin in cosmetic products will also inevitably increase the risk of cosmetic dermatitis in consumers allergic to formaldehyde."[3] DMDM hydantoin may cause allergic contact dermatitis to the product itself, cross-react with other formaldehyde releasing compounds or due to the formaldehyde released.[citation needed]


  1. ^ Record in the Household Products Database of NLM
  2. ^ DMDM Hydantoin at
  3. ^ de Groot AC, van Joost T, Bos JD, van der Meeren HL, Weyland JW (1988). "Patch test reactivity to DMDM hydantoin. Relationship to formaldehyde allergy". Contact Dermatitis 18 (4): 197–201. doi:10.1111/j.1600-0536.1988.tb02802.x. PMID 3378426.