DMDM hydantoin

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DMDM hydantoin
DMDM hydantoin.svg
IUPAC name
Other names
Abbreviations DMDMH
CAS number 6440-58-0 YesY
ChemSpider 21482 YesY
EC number 229-222-8
Jmol-3D images Image
PubChem 22947
Molar mass 188.18 g/mol
EU classification Irritant Xi
R-phrases R43
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

DMDM hydantoin is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. DMDM hydantoin is an organic compound belonging to a class of compounds known as hydantoins. It is used in the cosmetics industry and found in products like shampoos, hair conditioners, hair gels, Rite Aid Liquid Lubricant, and skin care products.[1][2]

DMDM hydantoin works as a preservative because the released formaldehyde makes the environment less favorable to the microorganisms.


A patch test study found "An increase in the use of DMDM hydantoin in cosmetic products will also inevitably increase the risk of cosmetic dermatitis in consumers allergic to formaldehyde."[3] DMDM hydantoin may cause allergic contact dermatitis to the product itself, cross-react with other formaldehyde releasing compounds or due to the formaldehyde released.[citation needed]


  1. ^ Record in the Household Products Database of NLM
  2. ^ DMDM Hydantoin at
  3. ^ de Groot AC, van Joost T, Bos JD, van der Meeren HL, Weyland JW (1988). "Patch test reactivity to DMDM hydantoin. Relationship to formaldehyde allergy". Contact Dermatitis 18 (4): 197–201. doi:10.1111/j.1600-0536.1988.tb02802.x. PMID 3378426.