DNAJA2

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DnaJ (Hsp40) homolog, subfamily A, member 2
Identifiers
Symbols DNAJA2 ; CPR3; DJ3; DJA2; DNAJ; DNJ3; HIRIP4; PRO3015; RDJ2
External IDs OMIM611322 MGI1931882 HomoloGene21193 GeneCards: DNAJA2 Gene
RNA expression pattern
PBB GE DNAJA2 209157 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10294 56445
Ensembl ENSG00000069345 ENSMUSG00000031701
UniProt O60884 Q9QYJ0
RefSeq (mRNA) NM_005880 NM_019794
RefSeq (protein) NP_005871 NP_062768
Location (UCSC) Chr 16:
46.99 – 47.01 Mb
Chr 8:
85.54 – 85.56 Mb
PubMed search [1] [2]

DnaJ homolog subfamily A member 2 is a protein that in humans is encoded by the DNAJA2 gene.[1][2][3]

The protein encoded by this gene shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of this protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding interacting proteins, HIRIPs, have been identified. HIRIP4 was isolated by virtue of its interaction with this protein; however, its exact function is not known. The sequence of HIRIP4 protein is highly homologous to the human DNJ3/CPR3, mouse Dj3 and rat Dj2 gene products.[3]

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