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DnaJ (Hsp40) homolog, subfamily A, member 3
Protein DNAJA3 PDB 2ctt.png
PDB rendering based on 2ctt.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols DNAJA3 ; HCA57; TID1; hTID-1
External IDs OMIM608382 MGI1933786 HomoloGene36170 GeneCards: DNAJA3 Gene
RNA expression pattern
PBB GE DNAJA3 205963 s at tn.png
More reference expression data
Species Human Mouse
Entrez 9093 83945
Ensembl ENSG00000103423 ENSMUSG00000004069
UniProt Q96EY1 Q99M87
RefSeq (mRNA) NM_001135110 NM_001135112
RefSeq (protein) NP_001128582 NP_001128584
Location (UCSC) Chr 16:
4.48 – 4.51 Mb
Chr 16:
4.64 – 4.71 Mb
PubMed search [1] [2]

DnaJ homolog subfamily A member 3, mitochondrial is a protein that in humans is encoded by the DNAJA3 gene.[1]


DNAJA3 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family, see MIM 608375.[supplied by OMIM][2]


DNAJA3 has been shown to interact with:


  1. ^ Schilling B, De-Medina T, Syken J, Vidal M, Munger K (August 1998). "A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein". Virology 247 (1): 74–85. doi:10.1006/viro.1998.9220. PMID 9683573. 
  2. ^ "Entrez Gene: DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3". 
  3. ^ a b Sarkar S, Pollack BP, Lin KT, Kotenko SV, Cook JR, Lewis A, Pestka S (December 2001). "hTid-1, a human DnaJ protein, modulates the interferon signaling pathway". J. Biol. Chem. 276 (52): 49034–42. doi:10.1074/jbc.M103683200. PMID 11679576. 
  4. ^ Trentin GA, Yin X, Tahir S, Lhotak S, Farhang-Fallah J, Li Y, Rozakis-Adcock M (April 2001). "A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein". J. Biol. Chem. 276 (16): 13087–95. doi:10.1074/jbc.M009267200. PMID 11116152. 

Further reading[edit]