DNPEP

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Aspartyl aminopeptidase
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols DNPEP ; ASPEP; DAP
External IDs OMIM611367 MGI1278328 HomoloGene6110 ChEMBL: 2761 GeneCards: DNPEP Gene
EC number 3.4.11.21
RNA expression pattern
PBB GE DNPEP 38703 at tn.png
PBB GE DNPEP 201937 s at tn.png
PBB GE DNPEP 217604 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23549 13437
Ensembl ENSG00000123992 ENSMUSG00000026209
UniProt Q9ULA0 Q9Z2W0
RefSeq (mRNA) NM_012100 NM_001110831
RefSeq (protein) NP_036232 NP_001104301
Location (UCSC) Chr 2:
220.24 – 220.26 Mb
Chr 1:
75.31 – 75.32 Mb
PubMed search [1] [2]

Aspartyl aminopeptidase is an enzyme that in humans is encoded by the DNPEP gene.[1][2]

The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins.[2]

References[edit]

  1. ^ Wilk S, Wilk E, Magnusson RP (Aug 1998). "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase". J Biol Chem 273 (26): 15961–70. doi:10.1074/jbc.273.26.15961. PMID 9632644. 
  2. ^ a b "Entrez Gene: DNPEP aspartyl aminopeptidase". 

Further reading[edit]

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: M18.002