DOT1L

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DOT1-like histone H3K79 methyltransferase
Protein DOT1L PDB 1nw3.png
PDB rendering based on 1nw3.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols DOT1L ; DOT1; KMT4
External IDs OMIM607375 MGI2143886 HomoloGene32779 ChEMBL: 1795117 GeneCards: DOT1L Gene
EC number 2.1.1.43
RNA expression pattern
PBB GE DOT1L 214865 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 84444 208266
Ensembl ENSG00000104885 ENSMUSG00000061589
UniProt Q8TEK3 Q6XZL8
RefSeq (mRNA) NM_032482 NM_199322
RefSeq (protein) NP_115871 NP_955354
Location (UCSC) Chr 19:
2.16 – 2.23 Mb
Chr 10:
80.76 – 80.8 Mb
PubMed search [1] [2]

DOT1-like, histone H3 methyltransferase (S. cerevisiae), also known as DOT1L, is a protein found in humans, as well as other eukaryotes.[1]


References[edit]

Further reading[edit]