DPEP3

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Dipeptidase 3
Identifiers
Symbols DPEP3 ; MBD3
External IDs OMIM609926 MGI1919104 HomoloGene23357 GeneCards: DPEP3 Gene
EC number 3.4.13.19
Orthologs
Species Human Mouse
Entrez 64180 71854
Ensembl ENSG00000141096 ENSMUSG00000031898
UniProt Q9H4B8 Q9DA79
RefSeq (mRNA) NM_001129758 NM_027960
RefSeq (protein) NP_001123230 NP_082236
Location (UCSC) Chr 16:
68.01 – 68.01 Mb
Chr 8:
105.97 – 105.98 Mb
PubMed search [1] [2]

Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene.[1]

This gene encodes a membrane-bound glycoprotein from the family of dipeptidases (EC 3.4.13.19) involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family, DPEP2. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.[2]

References[edit]

  1. ^ Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806. 
  2. ^ "Entrez Gene: Dipeptidase 3". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.