DPYSL2

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Dihydropyrimidinase-like 2
Protein DPYSL2 PDB 2gse.png
PDB rendering based on 2gse.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols DPYSL2 ; CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
External IDs OMIM602463 MGI1349763 HomoloGene74392 GeneCards: DPYSL2 Gene
RNA expression pattern
PBB GE DPYSL2 200762 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1808 12934
Ensembl ENSG00000092964 ENSMUSG00000022048
UniProt Q16555 O08553
RefSeq (mRNA) NM_001197293 NM_009955
RefSeq (protein) NP_001184222 NP_034085
Location (UCSC) Chr 8:
26.37 – 26.52 Mb
Chr 14:
66.8 – 66.87 Mb
PubMed search [1] [2]

Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene.[1][2]


Interactions[edit]

DPYSL2 has been shown to interact with CRMP1,[3] Adaptor-related protein complex 2, alpha 1[4] and NUMB.[4]

References[edit]

  1. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene 180 (1–2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361. 
  2. ^ "Entrez Gene: DPYSL2 dihydropyrimidinase-like 2". 
  3. ^ Leung, Thomas; Ng Yvonne; Cheong Albert; Ng Chong Han; Tan Ivan; Hall Christine; Lim Louis (Dec 2002). "p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology". FEBS Lett. (Netherlands) 532 (3): 445–9. doi:10.1016/S0014-5793(02)03736-5. ISSN 0014-5793. PMID 12482610. 
  4. ^ a b Nishimura, Takashi; Fukata Yuko; Kato Katsuhiro; Yamaguchi Tomoya; Matsuura Yoshiharu; Kamiguchi Hiroyuki; Kaibuchi Kozo (Sep 2003). "CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth". Nat. Cell Biol. (England) 5 (9): 819–26. doi:10.1038/ncb1039. ISSN 1465-7392. PMID 12942088. 

Further reading[edit]