David Ho (scientist)
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November 3, 1952 |
|Residence||Chappaqua, New York|
|Other names||David Da-i Ho, 何大一|
|Education||California Institute of Technology and Harvard-MIT Division of Health Sciences and Technology University of California, Los Angeles (UCLA)|
|Known for||AIDS research|
|Spouse(s)||Susan Kuo Ho|
|Parents||Paul Ho and Sonia Jiang|
David Da-i Ho (Chinese: 何大一; born November 3, 1952) is a Taiwanese American HIV/AIDS researcher famous for pioneering contributions to the understanding and treatment of HIV infection. He is the scientific director and chief executive officer of the Aaron Diamond AIDS Research Center and the Irene Diamond Professor at the Rockefeller University in New York.
David Ho was born in Taichung, Taiwan, to Paul (何步基, an engineer) and Sonia Ho (江雙如). David Ho attended Taichung Municipal Guang-Fu Elementary School until sixth grade before immigrating to the United States with his mother and younger brother to unite with his father, who had already been in the US since 1957. He grew up in Los Angeles He attended and graduated from John Marshall High School in Los Angeles, CA. He received his bachelor of science in physics with highest honors from the California Institute of Technology (1974) and MD from the Harvard-MIT Division of Health Sciences and Technology (1978). Subsequently, he did his clinical training in internal medicine and infectious diseases at UCLA School of Medicine (1978–1982) and Massachusetts General Hospital (1982–1985), respectively. He was a resident in internal medicine at Cedars-Sinai Medical Center in Los Angeles in 1981 when he came into contact with some of the first reported cases of what was later identified as AIDS.
Ho has been at the forefront of AIDS research for three decades. He published over 400 papers (cited June 2011), enabling the scientific community to understand the mechanism of HIV replication. He championed the combination anti-retroviral therapy which had earlier been developed by scientists at NIAID and Merck. This approach allowed the control of HIV replication in patients. AIDS mortality has declined six times in developed countries since 1996, and international efforts are under way to bring the treatment to patients in the developing world.
Ho shifted his work from treating late in the illness to finding ways to fight the disease early on. Ho helped devise the HAART or highly active anti-retroviral therapy, which prescribes a cocktail of drugs to treat AIDS, on the theory that it would be more effective to combine powerful protease inhibitors with other HIV medications.
Ho's research team is working on developing vaccines for AIDS. He heads a consortium of organization in China and the U.S. to address the crisis of HIV/AIDS in China. In a June 13, 2011 interview with Asian Scientist Magazine, he discusses his team's progress with Ibalizumab, the antibody his team is developing for HIV vaccination with support from the Gates Foundation.
Ho keeps good relations with the Taiwanese government and the top research institution of Taiwan, Academia Sinica. He has been playing important role in the state-sponsored research and development of biotechnology in Taiwan.
Honors and titles
Ho has received numerous honors and awards for his scientific accomplishments. He is the recipient of 12 honorary doctorates, including those from Columbia University and Tsinghua University. On January 8, 2001, he was presented with the Presidential Citizens Medal by President Clinton.
Ho was the chosen commencement speaker at Caltech, MIT, and Harvard School of Public Health.[when?] Other accolades include the Ernst Jung Prize in Medicine, Mayor’s Award for Excellence in Science & Technology, the Squibb Award, and the Hoechst Marion Roussel Award.
Ho is an honorary professor at Peking Union Medical College, Chinese Academy of Medical Sciences, Chinese Academy of Sciences, University of Hong Kong, Wuhan University, and Fudan University. He was a member of the Board of Overseers of Harvard University and the Board of Trustees of the California Institute of Technology. He is a board member of the Massachusetts Institute of Technology Corporation.
Ho was Time magazine's 1996 Man of the Year. Time later recalled the selection surprised both Ho and readers, with one reader calling Ho "Dr. David Who?" The magazine acknowledged in 1996 that "Ho is not, to be sure, a household name. But some people make headlines while others make history." Ho was even briefly mentioned when Alexander Fleming was considered for Person of the Century in 1999, since Fleming could be portrayed as representative of other disease-fighting scientists including Ho, but the title ultimately went to Albert Einstein.
On December 6, 2006, California governor Arnold Schwarzenegger and First Lady Maria Shriver inducted Ho into the California Hall of Fame located at The California Museum for History, Women, and the Arts.
Ho and his wife, artist Susan Kuo Ho, live in New York and have three children: Kathryn, Jonathan, and Jaclyn.
- Sen. Russ Feingold (D-WI) noted, "Without the contributions of Taiwanese Americans, we would lack the important AIDS research of Dr. David Ho., Formosan Association for Public Affairs, MAY 2000
- The Taiwanese Americans, page 130-131
- Taiwanese-American HIV/AIDS academic joins team, The Taipei Times, Sep 04, 2011
- U.S. PUBLIC TV STATIONS TO BROADCAST TAIWAN TRAVEL FEATURES, Government Information Office, Republic of China (Taiwan), 12/27/2006
- Park, Alice (2010-01-25). "Scientist David Ho: The Man Who Could Beat AIDS". Time. Retrieved 24 January 2010.
- "Caltech Commencement Program". Caltech Campus Publications. 1974-06-14. Retrieved 2013-03-29.
- (Nature 1995; Science 1996)
- (N. Engl. J. Med. 1995; Science 1996)
- "Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy". 1997. doi:10.1056/NEJM199709113371102.
- (Nature 1997)
- "AIDS Research Pioneer, David Ho, Talks To Asian Scientist Magazine". Asian Scientist Magazine. June 13, 2011.
- President Lee Teng-hui Meets with Dr. David Ho, Office of the President, Republic of China (Taiwan), 1997/01/30
- Let's Travel to Taiwan 台灣旅遊專題新節目「台灣：宜人之處」發表會, The Taipei Economic and Cultural Office in New York, 2011/3/11
- Shining Brightly on the Global Stage, Government Information Office of Taiwan
- David Ho agrees to head biotech committee, The Taipei Times, Apr 18, 2000
- Tsai Ing-wen to lead new state-sponsored bio-tech firm, Government Information Office, Republic of China (Taiwan), 09/13/2007
- "TaiMed, Genentech tie up in biopharmaceutical research". Government Information Office, Republic of China (Taiwan), September 27, 2007
- Mo, Steven (June 13, 2011). "AIDS Research Pioneer, David Ho, Talks To Asian Scientist Magazine". Asian Scientist.
- Time, Person of the Year: 75th Anniversary Celebration, Special Collector's Edition, Time Books, 2002, p. 108.
- Time Millennium, Collector's Edition, Time Inc. Specials, p. 21.
|Wikimedia Commons has media related to David Ho.|
- Rockefeller Heads of Laboratories
- 1996 Man of the Year
- Aaron Diamond AIDS Research Center
- Ubben Lecture at DePauw University; April 16, 1997
- David Ho Interview -- Academy of Achievement