By trade David Joris was a glass painter or tinsel painter, having learned the art in Antwerp. In 1524 he married Dirckgen Willems, and also took interest in the Reformation movement of Martin Luther. In 1533 he accepted the ideas of the Anabaptists, and was baptized in Delft by Obbe Philips. According to the Mennonite Encyclopedia, "He was an influential figure in Anabaptism's consolidation period following the fall of Münster." He rejected the violence of Münster, but theoretically accepted polygamy (he is not known to have practiced it). After the Münster debacle, a number of diverse disciples of Hoffman gathered for counsel at Bocholt in 1536. Joris had some success in highlighting their common beliefs, while diffusing the ideas of those who wanted vengeance. He believed that God would take vengeance, but that the saints should not. He promoted compromise on the question of polygamy, stating he thought the number of wives a man had was not important, as long as the family obeyed God. The group made no decision on the issue. David Joris remained on the "mystic" edge of Anabaptism, leading by citing dreams, visions and prophecies. Against this is his rationalist approach to the topic of the devil and supernatural evil. David Joris anticipated the views of Thomas Hobbes, John Epps and John Thomas in interpreting the devil as an allegory.
For a time he was a theological combatant with emerging leader Menno Simons. Menno considered Joris a compromiser; Joris thought Menno excessively literal. Joris moved to Basel in 1544 and protected himself by living under the assumed name Johann van Brugge. He joined the Reformed Church, but he continued his theological writings on Anabaptism. This reflects both his opinion that "to the pure all things are pure", and his developing view that external symbols were less important than inner faith.
His wife Dirckgen died 22 August 1556. David died three days later and was buried in the church of St Leonard, Basel. Anabaptist leader Nicolas van Blesdijk, the husband of his eldest daughter, became an opponent of Joris' teachings. In 1559 he revealed Joris' theology to the authorities of Basel. David Joris was posthumously convicted of heresy, and his body exhumed and burned on 13 May 1559. A portrait of Joris, by the Dutch painter Jan van Scorel, is now displayed in the Oeffentliche Kunstsammlung at Basel.
The Mennonite Encyclopedia divides Joris' religious career into "four overlapping phases: Sacramentarian (1524–1530); Melchiorite sympathizer (1531–1534) Anabaptist leader (1534–c. 1543); and Spiritualist (c. 1540–1556)." In addition to his spiritualism, Joris developed nicodemite practices from 1534 on.
- "Man is a Devil to Himself"
His writings number over 200.
- David Joris and Dutch Anabaptism, 1524-1543
- Stuart Clark Thinking with demons: the idea of witchcraft in early modern Europe 1999 Page 543
- Gary K. Waite, "Man is a Devil to Himself": David Joris and the Rise of a Sceptical Tradition towards the Devil in the Early Modern Netherlands
- Waite, Gary K. (1990). "From Anabaptist to Nicodemite, 1534-39". David Joris and Dutch Anabaptism, 1524–1543. Waterloo, ON: Wilfrid Laurier University Press.
- The Anabaptist Writings of David Joris, 1535–1543, "Classics of the Radical Reformation, Vol. 7", edited by Gary K. Waite, Scottsdale, PA: Herald Press 1993; ISBN 0-8361-3113-4
- Becoming Anabaptist: The Origin and Significance of Sixteenth-Century Anabaptism, J. Denny Weaver, Scottsdale, PA: Herald Press 1987 ISBN 0-8361-3434-6
- David Joris and Dutch Anabaptism, 1524–1543, Gary K. Waite, Waterloo, ON: Wilfrid Laurier University Press 1990
- David Joris in Global Anabaptist Mennonite Encyclopedia Online
-  German written biography of David Joris on altbasel.ch