Her work includes her two hit Christmas Comedy films "Nativity! and "Nativity 2 Danger in the Manger". She is also known for her Bafta award winning teleplay The Illustrated Mum, the stage play The Woman Who Cooked Her Husband and the feature films Nasty Neighbours,Confetti Fox Searchlight. Most recently Debbie directed the ITV series Love and Marriage.
Nativity!, her third feature film starring Martin Freeman, was released in November 2009 and became the most successful Independent British film of the year. The sequel, and her fourth film, Nativity 2: Danger in the Manger starred David Tennant and was released in November 2012 and was an instant box office hit making twice the amount at the UK box office as the original film.
Isitt has now completed the trilogy with Nativity 3 "Dude Where's My Donkey!"