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Degradation may refer to:
- Biodegradation, the processes by which organic substances are broken down by living organisms
- Cashiering or degradation ceremony, a ritual performed when cleric is deprived of office or a knight is stripped of the honour
- Chemical decomposition, the degradation of chemical compounds
- Corruption (philosophical concept)
- Degradation (geology)
- "Degradation", a song by the Violent Femmes, from Add It Up (1981–1993)
- Degradation (telecommunications), the loss of quality of an electronic signal
- Elegant degradation, in engineering, the gradual and manageable, rather than sudden or catastrophic, failure of a machine
- Environmental degradation, in ecology, damage to the ecosystem and loss of biodiversity
- Graceful degradation, in a fault-tolerant system
- Polymer degradation, usually undesirable, though sometimes deliberate, chemical and physical changes in plastics and similar materials as they age
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