Demecarium bromide

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Demecarium bromide
Demecarium bromide.png
Systematic (IUPAC) name
trimethyl-[3-[methyl-[10-[methyl- (3-trimethylammoniophenoxy) carbonyl-amino] decyl] carbamoyl] oxyphenyl]-ammonium dibromide
Clinical data
Legal status
?
Identifiers
CAS number 56-94-0 YesY
ATC code S01EB04
PubChem CID 5965
DrugBank DB00944
ChemSpider 5750 YesY
UNII 61D5V4OKTP YesY
KEGG D00667 YesY
ChEBI CHEBI:4391 YesY
ChEMBL CHEMBL1200514 N
Chemical data
Formula C32H52Br2N4O4 
Mol. mass 716.588 g/mol
 N (what is this?)  (verify)

Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals.[1][2][3]

See also[edit]

References[edit]

  1. ^ Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs.". Vet Ophthalmol 6 (1): 23–5. doi:10.1046/j.1463-5224.2003.00257.x. PMID 12641839. 
  2. ^ Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs.". Am J Vet Res 55 (12): 1729–33. PMID 7887518. 
  3. ^ Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma.". Am J Vet Res 54 (2): 287–93. PMID 8430939.