Dennis Bray

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Dennis Bray
Residence UK
Nationality British
Fields computational biology, microbiology, neurobiology
Institutions University of Cambridge
Notable awards Microsoft European Science Award (2007)

Dennis Bray is an active emeritus professor at University of Cambridge. His group is also part of the Oxford Centre for Integrative Systems Biology. After a first career in Neurobiology, working on cell growth and movement, Dennis Bray moved in Cambridge to develop computational models of cell signaling, in particular in relation to bacterial chemotaxis.

On November 3, 2006, he was awarded the Microsoft European Science Award for his work on chemotaxis of E. coli.[1][2]

Books[edit]

In this book Bray offers imaginative, wide-ranging and perceptive critiques of robotics and complexity theory, as well as many amusing and telling anecdotes. The book taps into the findings of the new discipline of systems biology to show that the internal chemistry of living cells is a form of computation, although that sounds consuming it is written very clearly and understandably. How does a single-cell creature, such as an amoeba, lead such a sophisticated life? How does it hunt living prey, respond to lights, sounds, and smells, and display complex sequences of movements without the benefit of a nervous system? Bray proposes a startling and original answer. Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis of all the distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence.[3]

Main scientific publications[edit]

  • Bray D (1970) Surface movements during growth of single explanted neurons. Proc Natl Acad Sci USA, 65: 905
  • Bray D, White JG (1988) Cortical flow in animal cells. Science, 239: 883-888
  • Bray D (1995) Protein molecules as computational elements in living cells. Nature, 376: 307-312
  • Bray D, Levin MD, Morton-Firth CJ (1998) Receptor clustering as a cellular mechanism to control sensitivity. Nature, 393: 85-88

Mention in Popular Science[edit]

Professor Franklin M. Harold writes "The theme [of a protein's shape and functionality being altered by interaction with its environment] comes with numerous variations, some of which are discussed in a thought-provoking article by Dennis Bray [author references Dr. Bray's 1995 article] that examines proteins as information-processing devices."[4]

References[edit]

  1. ^ http://research.microsoft.com/displayArticle.aspx?id=1572 retrieved November 6, 2006
  2. ^ http://news.bbc.co.uk/2/hi/science/nature/6113522.stm retrieved November 6, 2006
  3. ^ http://www.kurzweilai.net/wetware-a-computer-in-every-living-cell
  4. ^ Harold, Franklin M. (2001). The way of the cell: molecules, organisms, and the order of life. New York: Oxford University Press. p. 76. ISBN 0-19-513512-1. 

External links[edit]