Benign fibrous histiocytoma

From Wikipedia, the free encyclopedia

  (Redirected from Dermatofibroma)
Jump to: navigation, search
Dermatofibroma
Classification and external resources
ICD-10 D23..-
ICD-9 216.9
ICD-O: M8830/0
DiseasesDB 29384
eMedicine derm/96 
MeSH D018219

Benign fibrous histiocytomas (also known as "Dermatofibroma," "Fibrous dermatofibroma," and "Fibrous histiocytoma"[1]:668) are benign skin growths.[2]

[edit] Presentation

Dermatofibromas are hard papules (rounded bumps) that may appear in a variety of colors, usually brownish to tan. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.[3] They are composed of disordered collagen laid down by fibroblasts. In rare cases, basal cell carcinoma may develop in a dermatofibroma.

They are usually found on the leg.[4]

Deep penetrating dermatofibroma may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.[5]

Dermatofibromas occur most often in women; the male to female ratio is about 1:4.[3]

[edit] See also

[edit] References

  1. ^ Freedberg, et. al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
  2. ^ benign fibrous histiocytoma at Dorland's Medical Dictionary
  3. ^ a b Pierson, Joseph C.; Diane M Pierson. "Dermatofibroma". eMedicine. WebMD. http://emedicine.medscape.com/article/1056742-overview. Retrieved on 2009-06-13. 
  4. ^ dermatofibroma at Dorland's Medical Dictionary
  5. ^ Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M (June 2006). "High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors". Archives of pathology & laboratory medicine 130 (6): 831–4. PMID 16740036. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=130&page=831. 
Personal tools