Dermatographic urticaria
| Dermatographic urticaria | |
|---|---|
| Classification and external resources | |
 Dermatographic urticaria is sometimes called "skin writing". |
|
| ICD-10 | L50.3 |
| ICD-9 | 708.3 |
| OMIM | 125635 |
| DiseasesDB | 12736 |
| eMedicine | derm/446 |
Dermatographic urticaria (also known as dermographism, dermatographism or "skin writing") is a skin disorder seen in 4–5% of the population and is one of the most common types of urticaria,[1] in which the skin becomes raised and inflamed when stroked, scratched, rubbed, and sometimes even slapped.[2] It is most common in young adults, ages 20-30.[citation needed]
Contents |
Presentation[edit]
The symptoms are thought to be caused by mast cells in the surface of the skin releasing histamines without the presence of antigens, due to the presence of a weak membrane surrounding the mast cells. The histamines released cause the skin to swell in the affected areas.
This weak membrane easily and rapidly breaks down under physical pressure causing an allergic-like reaction, in general a red wheal (welt) to appear on the skin. It can often be confused with an allergic reaction to the object causing a scratch, when in fact it is the act of being scratched that causes a wheal to appear. These wheals are a subset of urticaria (hives) that appear within minutes, in some cases accompanied with itching. The first outbreak of urticaria can lead to others on body parts not directly stimulated, scraped, or scratched. In a normal case, the swelling will reduce itself with no treatment within 15–30 minutes, but, in extreme cases, itchy red wheals may last anywhere from a few hours to days.
Causes[edit]
The underlying cause of dermographism is not known, and can last for many years without relief. Ninety-five percent of chronic cases are never solved. Increased incidence has been observed following prolonged exposure to microwaves.[3][4] Sometimes the condition goes away, sometimes it stays forever. It is not a life-threatening disease and is not contagious.
Symptoms can be induced by periods of physical stress, tight or abrasive clothing, watches, glasses, heat, cold,[5] or anything that causes stress to the skin or the patient.
Treatment[edit]
Dermographism can be treated by substances, which prevent histamine from causing the reaction. These may need to be given as a combination of H1 antagonists, or possibly with an H2-receptor antagonist such as cimetidine.[6][7]
Not taking hot baths or showers may help if it is generalized (all over) and possibly for localized (in a specific area). If not taking hot showers helps, it may be a condition called shower eczema. If it affects mainly the head, it may be psoriasis. In rare cases, allergy tests may uncover substances the patient is allergic to. Using biodegradable or hypo-allergenic soaps and laundry supplies may help.
While cromoglycate, which prevents histamine from being released from mast cells, is used topically in rhinitis and asthma, it is not effective orally for treating chronic urticaria. Bug spray may also cause the reaction to the skin.[8][9]
Frequent anecdotal evidence suggests taking in small amounts of alcohol may help with the itching, or temporarily cause the inflammation/welts to subside.
Acupuncture and Chinese herbs have long been used to treat urticaria in the Asian world. Results of clinical trials of both acupuncture and Chinese herbs are inconclusive and are possibly a result of the placebo effect, as the trials did not involve a control group.[10][11][12]
See also[edit]
References[edit]
- ^ Jedele KB, Michels VV (1991). "Familial dermographism". Am. J. Med. Genet. 39 (2): 201–3. doi:10.1002/ajmg.1320390216. PMID 2063925.
- ^ Kontou-Fili K, Borici-Mazi R, Kapp A, Matjevic LJ, Mitchel FB (1997). "Physical urticaria: classification and diagnostic guidelines. An EAACI position paper". Allergy 52 (5): 504–13. doi:10.1111/j.1398-9995.1997.tb02593.x. PMID 9201361.
- ^ "Sadcikova Clinical manifestations of reactions to microwave irradiation in various occupational groups 1973". Retrieved 6 May 2012.
- ^ B. Hocking (February 2001). "Microwave sickness: a reappraisal". Occupational medicine (Oxford, England) 51 (1): 66–69. PMID 11235831.
- ^ Kaplan AP (1984). "Unusual cold-induced disorders: cold-dependent dermatographism and systemic cold urticaria". J Allergy Clin Immunol 73 (4): 453–6. doi:10.1016/0091-6749(84)90354-3. PMID 6200525.
- ^ Wozel G, Sahre EM, Barth J (1990). "[Effectiveness of combination treatment with H1-(Tavegyl) and H2-antagonists (Altramet) in chronic/chronically-recurrent urticaria]". Dermatologische Monatschrift (in German) 176 (11): 653–9. PMID 2083605.
- ^ Negro-Alvarez JM, Miralles-López JC (2001). "Chronic idiopathic urticaria treatment" ([dead link] – Scholar search). Allergologia et immunopathologia 29 (4): 129–32. PMID 11674926.
- ^ Thormann J, Laurberg G, Zachariae H (March 1980). "Oral sodium cromoglycate in chronic urticaria". Allergy 35 (2): 139–41. doi:10.1111/j.1398-9995.1980.tb01728.x. PMID 6770707.
- ^ Soter NA (December 1990). "Urticaria: current therapy". The Journal of allergy and clinical immunology 86 (6 Pt 2): 1009–14. doi:10.1016/S0091-6749(05)80245-3. PMID 1979795.
- ^ Jianli Che (2006). "The Effect of Acupuncture on Serum IgE Level in Patients with Chronic Urticaria". Journal of Traditional Chinese Medicine 26 (3): 189–190. PMID 17078446.
- ^ Chung-Jen Chen MD, Hsin-Su Yu MD PhD (1998). "Acupuncture Treatment of Urticaria". Archives of Dermatolology 134 (11): 1397–1399. doi:10.1001/archderm.134.11.1397. PMID 9828874.
- ^ Benjamin Kligler, Roberta A. Lee (April 2004). Integrative medicine: principles for practice 134. McGraw-Hill Professional. pp. 371–377. ISBN 978-0-07-140239-2. Unknown parameter
|isbn-13=ignored (help); Unknown parameter|isbn-10=ignored (help)
|
||||||||||||||||||||||||||||||||
