Desmolase
From Wikipedia, the free encyclopedia
Desmolase is an enzyme that catalyzes the formation or destruction of carbon-carbon bonds within a molecule. This enzyme plays a significant role in respiration and fermentation.
Desmolases are a group enzymes involved in steroidogenesis. Examples are:
- Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone.
- 17,20 desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17-hydroxypregnenolone, progesterone to 17-hydroxyprogesterone, and corticosterone to cortisol.
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