Desonide

Desonide

Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Clinical data
Trade names	Desowen
AHFS/Drugs.com	monograph
MedlinePlus	a605025
Pregnancy cat.	C(US)
Legal status	?
Routes	topical
Identifiers
CAS number	638-94-8 Y
ATC code	S01BA11
PubChem	CID 12536
DrugBank	DB01260
ChemSpider	4470603 Y
UNII	J280872D1O Y
KEGG	D03696 Y
ChEBI	CHEBI:204734 Y
ChEMBL	CHEMBL1201109 N
Synonyms	(11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Chemical data
Formula	C24H32O6
Mol. mass	416.507
SMILES	eMolecules & PubChem
InChI InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1 Y Key:WBGKWQHBNHJJPZ-LECWWXJVSA-N Y
N(what is this?)  (verify)

Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, psoriasis and contact dermatitis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam.