Desonide

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Desonide
Desonide.png
Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Clinical data
Trade names Desowen
AHFS/Drugs.com monograph
MedlinePlus a605025
  • US: C (Risk not ruled out)
topical
Identifiers
638-94-8 YesY
D07AB08 S01BA11
PubChem CID 12536
DrugBank DB01260 YesY
ChemSpider 4470603 YesY
UNII J280872D1O YesY
KEGG D03696 YesY
ChEBI CHEBI:204734 YesY
ChEMBL CHEMBL1201109 N
Synonyms (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Chemical data
Formula C24H32O6
416.507 g/mol
 N (what is this?)  (verify)

Desonide is the generic name of a low-potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile[1] and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. It is a group VI corticosteroid under US classification, the second least potent group.

References[edit]

  1. ^ Wong, Vicky Kwan; Brian Fuchs, Mark Lebwohl (2004). "Overview on desonide 0.05%: a clinical safety profile". Journal of Drugs in Dermatology: JDD 3 (4): 393–7. PMID 15303783.