Dexetimide

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Dexetimide
Dexetimide.svg
Systematic (IUPAC) name
3-(1-benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 21888-98-2 N
ATC code N04AA08
PubChem CID 30843
IUPHAR ligand 354
ChemSpider 28615 YesY
UNII 43477QYX3D YesY
KEGG D03711 YesY
ChEMBL CHEMBL273974 N
Chemical data
Formula C23H26N2O2 
Mol. mass 362.465 g/mol
 N (what is this?)  (verify)

Dexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced Parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.[1][2]

References[edit]

  1. ^ Dom, R.; Van Lommel, R.; Baro, F. (1971). "A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent". Acta Psychiatrica Scandinavica 47 (4): 399–410. PMID 4947805.  edit
  2. ^ Huygens, H.; Vereecken, J. L.; Tanghe, A. (1973). "Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action". Psychiatria, neurologia, neurochirurgia 76 (4): 251–259. PMID 4581374.  edit