Dexketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Enantyum, produced by Menarini. Also, in Italy and Spain it is available as an over the counter-drug under the tradename respectively Enantyum, Ketesgel. Both in Lithuania and Estonia it is available as over the counter-drug under tradename Dolmen. In Mexico it is available in tablet form as "Stadium" made by Menarini in Luxemburg.
Dexketoprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action.
This medicine may cause dizziness and so may affect your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance.
In the USA: Adult: 12.5 mg of ketoprofen every 4–6 hours as needed, or 25 mg every 8 hours as needed; max 75 mg daily. Elderly: initially max 50 mg daily as needed. Child: not recommended.
In Europe: As prescribed, the dosage is variable being consistent with the nature, severity and duration of the pain episode. Currently the prescribed amount is 25 mg every 8 hours, although the daily dosage should not exceed 75 mg. In elderly patients, light to moderate liver and renal failure, the maximum dosage is set at a maximum of 50 mg/24h. Dexketoprofen is currently not prescribed to children under the age of 18.