|Systematic (IUPAC) name|
|Pregnancy cat.||Lacking information|
|Metabolism||Hepatic: deacetylation to rhein, later glucuronidation and sulfate conjugation|
|Half-life||4 to 5 hours|
|Synonyms||Diacetylrhein; Diacerhein; 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-; 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-, diacetate; 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid, diacetate|
|Mol. mass||368.294 g/mol|
| (what is this?)
Diacerein (INN), also known as diacetylrhein, is a drug used in the treatment of osteoarthritis. It works by inhibiting interleukin-1. A 2005 Cochrane review found diacerein to be slightly, but significantly, more effective than placebo in improving pain and slowing the progress of osteoarthritis in the hip.
Side effects 
The dosage of diacerein is 50 mg twice daily, after meals, for 3 or more years.
It is marketed in Egypt and the Middle East by Evapharma. The Original product company was TRB Ltd Swiss. In Pakistan, it is marketed and sold as Diora (Getz Pharma). In Greece it has been sold since 2001 by Faran Ltd under the trade name Verboril.
See also 
- Harry Gouvas: Use of Sodium Hyaluronate in the treatment of Osteoarthritis, Greece, 2011
- Fidelix TS, Soares BG, Trevisani VF (2006). "Diacerein for osteoarthritis". In Fidelix, Tania S.A. Cochrane database of systematic reviews (Online) (1): CD005117. doi:10.1002/14651858.CD005117.pub2. PMID 16437519. Free summary
- (French) "Diacereine". BIAM. 1999-03-24. Retrieved 2007-06-13.
- Faran AE, Brochure of Diacerein (VERBORIL), 2001