Dibenzepin

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Dibenzepin
Systematic (IUPAC) name
10-(2-(dimethylamino)ethyl)-5-methyl-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one
Identifiers
CAS number 4498-32-2
ATC code N06AA08
PubChem 9419
Chemical data
Formula C18H21N3O 
Mol. mass 295.379
Pharmacokinetic data
Bioavailability 25% (oral)
Metabolism Hepatic, demethylation
Half life 5 h
Excretion Renal
Therapeutic considerations
Pregnancy cat.

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Legal status

POM/Rx

Routes Oral

Dibenzepin (Noveril) is a psychoactive drug of the tricyclic antidepressant (TCA) class of compounds that acts as a norepinephrine reuptake inhibitor (NRI), antihistamine, and anticholinergic. It is indicated for use as an antidepressant.[1] It has similar properties to imipramine and is considered either weakly or non-sedative.

[edit] References

  1. ^ Fachinformation (prescription information) for Noveril TR from Arzneimittel-Kompendium der Schweiz, [1], ret. on April 5th, 2008


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