Manzoni was signed by Parma on 31 August 2009 in a direct player swap, for €500,000. Francesco Pambianchi and Niccolò Galli moved to Pergocrema in co-ownership deal for a total fee of €500,000 (However both player had joined the club in January and July 2009 in co-ownership for peppercorn already, and Parma bought back for peppercorn and resold for a total of €500,000). Manzoni signed a 5-year contract. He did not had a shirt number in the first team nor had a place in the youth team (which played by overage player Stefano Russo instead) In 2010-11 season, he remained at Parma's youth team as overage player, however he did not played any game.
On 29 June 2011, 2 days before the closure of 2010–11 financial year of "Parma F.C. S.p.A.", he joined Genoa in co-ownership deal, for €1.7 million in 4-year contract, but in July returned to Parma on loan. However he still did not had a first team squad number and new signing Alberto Gallinetta became the third keeper of the team. The co-ownership was renewed in June 2012, 2013 and 2014.