On 30 July 2010, Mbokani signed a deal with French side AS Monaco.
On 9 August 2011, he signed a contract with Anderlecht for a reported fee of €3 million, stating that he looked forward to playing together again with his friend Milan Jovanović. The start of his spell at Anderlecht was dramatic, first injuring himself during one of his first training sessions, meaning he would be sidelined for at least two months. Then, about one week later his five month old son, David Mbokani, died of a cardiac arrest in his sleep.
On the 21st of June 2013, Mbokani had officially signed a contract with the Ukrainian club FC Dynamo Kyiv. On the 14th of July 2013, Mbokani scored his first goal in the very first game of the Ukrainian league against Volyn Lutsk on the 28th minute which ended 1-1.