Diflorasone

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Diflorasone
Diflorasone.png
Systematic (IUPAC) name
[17-(2-Acetyloxyacetyl)- 6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16- octahydrocyclopenta[a]phenanthren-17-yl] acetate
Clinical data
Trade names Psorcon
AHFS/Drugs.com monograph
MedlinePlus a602019
  • US: C (Risk not ruled out)
Topical
Identifiers
1-13-8 N
D07AC10
PubChem CID 71414
DrugBank DB00223 YesY
ChemSpider 64504 YesY
UNII T2DHJ9645W YesY
KEGG D01327 YesY
ChEBI CHEBI:31483 YesY
ChEMBL CHEMBL1201380 N
Chemical data
Formula C26H32F2O7
494.525 g/mol
 N (what is this?)  (verify)

Diflorasone is a topical steroid that comes in the form of a cream containing diflorasone diacetate. In is manufactured by E. Fougera & Co. and is used as an anti-inflammatory and anti-itching agent, like other topical corticosteroids. It is prescribed for psoriasis[1] and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a Class III steroid (of classes I–IV).[2]

No long-term animal studies have been done to determine whether diflorasone could have carcinogenic properties.[citation needed]

Little data is available regarding whether diflorasone would be present in great enough quantities to cause harm to an infant.[2]

References[edit]

  1. ^ Shupack, J. L.; Jondreau, L.; Kenny, C.; Stiller, M. J. (1993). "Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis". Dermatology (Basel, Switzerland) 186 (2): 129–132. PMID 8428041.  edit
  2. ^ a b Drugs.com: Diflorasone topical