|This article does not cite any references or sources. (November 2010)|
|Locus||Chr. 1 p22|
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation. It is the initial and rate-limiting step in pyrimidine catabolism. It catalyzes the reduction of uracil and thymine. It is also involved in the degradation of the chemotherapeutic drugs 5-fluorouracil and Tegafur-uracil.
|This enzyme-related article is a stub. You can help Wikipedia by expanding it.|