Dihydrotachysterol

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Not to be confused with Dihydrotestosterone.
Dihydrotachysterol
Dihydrotachysterol.png
Systematic (IUPAC) name
(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-Dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylcyclohexan-1-ol
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a682335
Legal status ?
Identifiers
CAS number 67-96-9 YesY
ATC code A11CC02
PubChem CID 5311071
DrugBank DB01070
ChemSpider 4470607 YesY
UNII R5LM3H112R YesY
KEGG D00299 YesY
ChEBI CHEBI:4591 YesY
Chemical data
Formula C28H46O 
Mol. mass 398.664 g/mol
 YesY (what is this?)  (verify)

Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.[1]

References[edit]

  1. ^ R. Gagnon, G. W. Ogden, G. Just, M. Kaye (1974). "Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure". Canadian Journal of Physiology and Pharmacology 52 (2): 272–274. doi:10.1139/y74-037. PMID 4365509.