Diiodotyrosine

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Diiodotyrosine
Diiodotyrosine.png
Identifiers
CAS number 66-02-4 YesY
PubChem 6181, 7058163
ChemSpider 8946 N
UNII 6L57Q44ZWW YesY
MeSH Diiodotyrosine
Jmol-3D images Image 1
Properties
Molecular formula C9H9I2NO3
Molar mass 432.982 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Diiodotyrosine (DIT) is a precursor in the production of thyroid hormone, and results from iodization of monoiodotyrosine at the other meta- position on the phenol ring.

Function[edit]

DIT is a modulator of the enzyme thyroid peroxidase (which is involved in the production of thyroid hormones).[1]

Triiodothyronine is formed, when diiodotyrosine is combined with monoiodotyrosine (in the colloid of the thyroid follicle).

Two molecules of DIT combine to make the thyroid hormone thyroxine ('T4' and 'T3').

See also[edit]

References[edit]

External links[edit]