Diiodotyrosine
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| Diiodotyrosine | |
|---|---|
| Identifiers | |
| CAS number | 66-02-4 |
| PubChem | 6181 |
| UNII | 6L57Q44ZWW |
| MeSH | Diiodotyrosine |
| Properties | |
| Molecular formula | C9H9I2NO3 |
| Molar mass | 432.982 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Diiodotyrosine (DIT) is a precursor of thyroid hormone and results from iodization of monoiodotyrosine at the other meta- position on the phenol ring.
DIT is a modulator of thyroid peroxidase.[1] When combined with monoiodotyrosine in the colloid of the thyroid follicle, triiodothyronine is formed. Two molecules of DIT combine to make thyroxine.
[edit] See also
[edit] References
- ^ Dème D, Fimiani E, Pommier J, Nunez J (February 1975). "Free diiodotyrosine effects on protein iodination and thyroid hormone synthesis catalyzed by thyroid peroxidase". Eur. J. Biochem. 51 (2): 329–36. doi:10.1111/j.1432-1033.1975.tb03932.x. PMID 1149735. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0014-2956&date=1975&volume=51&issue=2&spage=329.
[edit] External links
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