The club was founded on May 8, 1948 and has played exclusively at amateur level in all its history, making it the second team in the town after professional crosstown rivals Helmond Sport. The club was part of the Hoofdklasse league in the 2009–10 season, completing it in fifthplace in the Sunday B group, and then winning promotion to the newly established Topklasse league for the inaugural 2010–11 season through playoffs.
After a few months into the 2010-11 season, the main sponsor withdrew, leaving Dijkse Boys in financial trouble. In the turmoil, the club lost a KNVB Cup match against SC Genemuiden 1-9. The day after the defeat, Dijkse Boys decided to withdraw from the Topklasse because of financial problems.
The club was relegates to Hoofdklasse. As of the 2012-13 season the club plays in de Eerste Klasse. The fifth league on the Dutch football league pyramid.