Dimenoxadol

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Dimenoxadol
Dimenoxadol.svg
Systematic (IUPAC) name
2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate
Clinical data
Legal status Prohibited (S9) (AU) Schedule I (US)
Identifiers
CAS number 509-78-4 YesY
ATC code None
PubChem CID 17036
DrugBank DB01461
ChemSpider 16137 YesY
UNII 4D65PBX0VK YesY
Synonyms Dimenoxadol, Estocin
Chemical data
Formula C20H25NO3 
Mol. mass 327.42 g/mol
 YesY (what is this?)  (verify)

Dimenoxadol (INN; Estocin), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

It was invented in Germany in the 1950s,[1] and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.[2][3][4]

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9617 and a 2013 annual aggregrate manufacturing quota of zero.

References[edit]

  1. ^ GB 716700, Boehringer, A et al., "A new and improved analgesic and process for its production", published 10/13/1954 
  2. ^ Gorbatova, E. N. (1967). "The pharmacology of estocin, an new analgesic". Stomatologiia 46 (2): 22–25. PMID 5232927.  edit
  3. ^ Kingisepp, G. A.; Kurvits, K.; Nurmand, L. B. (1969). "Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin". Farmakologiia i toksikologiia 32 (6): 710–712. PMID 5381602.  edit
  4. ^ Liberman, S. S. (1968). "Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)". Farmakologiia i toksikologiia 31 (6): 668–671. PMID 5729519.  edit