Dimenoxadol

Dimenoxadol
Systematic (IUPAC) name
	2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate
Clinical data
Pregnancy cat.	?
Legal status	Prohibited (S9) (AU) Schedule I (US)
Identifiers
CAS number	509-78-4
ATC code	None
PubChem	CID 17036
DrugBank	DB01461
ChemSpider	16137
UNII	4D65PBX0VK
Synonyms	Dimenoxadol, Estocin
Chemical data
Formula	C20H25NO3
Mol. mass	327.42 g/mol
	SMILES Cl.CCOC(C(=O)OCCN(C)C)(c1ccccc1)c1ccccc1;
	InChI InChI=1S/C20H25NO3/c1-4-24-20(17-11-7-5-8-12-17,18-13-9-6-10-14-18)19(22)23-16-15-21(2)3/h5-14H,4,15-16H2,1-3H3 ; Key:RHUWRJWFHUKVED-UHFFFAOYSA-N ;
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Dimenoxadol (INN; Estocin), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

It was invented in Germany in the 1950s,^[1] and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.^[2]^[3]^[4]

References [edit]

^ GB 716700, Boehringer, A et al., "A new and improved analgesic and process for its production", published 10/13/1954
^ Gorbatova, E. N. (1967). "The pharmacology of estocin, an new analgesic". Stomatologiia 46 (2): 22–25. PMID 5232927. edit
^ Kingisepp, G. A.; Kurvits, K.; Nurmand, L. B. (1969). "Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin". Farmakologiia i toksikologiia 32 (6): 710–712. PMID 5381602. edit
^ Liberman, S. S. (1968). "Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)". Farmakologiia i toksikologiia 31 (6): 668–671. PMID 5729519. edit

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