Dipivefrine

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Dipivefrine

Systematic (IUPAC) name
[2-(2,2-dimethylpropanoyloxy)-4- (1-hydroxy-2-methylamino-ethyl)- phenyl] 2,2-dimethylpropanoate
Identifiers
CAS number	52365-63-6
ATC code	S01EA02
PubChem	3105
DrugBank	APRD00930
ChemSpider	2994
Chemical data
Formula	C19H29NO5
Mol. mass	351.437 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	B(US)
Legal status
Routes	?
Y(what is this?)  (verify)

Dipivefrine (Dipivefrin in the United States) is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution . It causes vasoconstriction, decreased aqueous humor production, and decreases intraoccular pressure. It gets converted to epinephrine upon penetrating the cornea.

v • d • e Ophthalmologicals: antiglaucoma preparations and miotics (S01E) Sympathomimetics Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine Parasympathomimetics muscarinic Aceclidine • Pilocarpine muscarinic/nicotinic Acetylcholine • Carbachol Acetylcholinesterase inhibitors Demecarium • Ecothiopate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon Carbonic anhydrase inhibitors/ (sulfonamides) Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide Beta blocking agents Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol Prostaglandin analogues (F2α) Bimatoprost • Latanoprost • Tafluprost • Travoprost • Unoprostone Other agents Dapiprazole • Guanethidine

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