|Systematic (IUPAC) name|
|[2-(2,2-dimethylpropanoyloxy)-4- (1-hydroxy-2-methylamino-ethyl)- phenyl] 2,2-dimethylpropanoate|
|Pregnancy cat.||B (US)|
|Mol. mass||351.437 g/mol|
| (what is this?)
Mechanism of action
The drug when applied over the cornea, penetrates it and is then hydrolysed to epinephrine by the esterases. It increases uveosacral outflow and also reduces aqueous formation (an α1 and α2 mediated action), thus reducing the intraocular pressure. It also increases the hydraulic conductivity of trabecular filtering cells (a β2 mediated action). It is preferred to epinephrine because it is longer acting, more consistent in its action and has better ocular tolerance.
PROPINE 0.1% eye drops.
|This article does not cite any references or sources. (March 2010)|
|This pharmacology-related article is a stub. You can help Wikipedia by expanding it.|