Disaccharidase
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Disaccharidases are glycoside hydrolases, enzymes that break down certain types of sugars called disaccharides into simpler sugars called monosaccharides. A genetic defect in one of these enzymes will cause a disaccharide intolerance, such as lactose intolerance or sucrose intolerance.
Examples of disaccharidases [edit]
- Lactase (breaks down lactose into glucose and galactose)
- Maltase (breaks down maltose into 2 glucoses)
- Sucrase (breaks down sucrose into glucose and fructose)
- Trehalase (breaks down trehalose into 2 glucoses)
For a thorough scientific overview of small-intestinal disaccharidases, one can consult chapter 75 of OMMBID.[1] For more online resources and references, see inborn error of metabolism.
References [edit]
- ^ Charles Scriver, Beaudet, A.L., Valle, D., Sly, W.S., Vogelstein, B., Childs, B., Kinzler, K.W. (Accessed 2007). The Online Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill. - Summaries of 255 chapters, full text through many universities. There is also the OMMBID blog.
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