Djedkhonsuefankh was a High Priest of Amun in Thebes from 1046-1045 BC. He was the second son of Pinedjem I. He succeeded his brother Masaherta during a time of great turmoil in the city of Thebes. Von Beckerath has suggested that it is possible that he died a violent death, accounting for his very short reign. He was succeeded by his half-brother Menkheperre.
His name is only known from the coffin of his son (now lost). His wife is likely to have been Djedmutesankh, a Singer of Amun, who was buried in Tomb MMA60 in Deir el-Bahari.