dnaC
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| DNA replication gene dnaC | |
|---|---|
| Identifiers | |
| Symbol | dnaC |
| Entrez | 948864 |
| UniProt | P0AEF0 |
| Other data | |
dnaC is a bacterial gene that codes for protein DnaC. DnaC, also known as the helicase loader, is a regulator of DnaB.[1] DnaC forms a complex with DnaB, thus enabling DnaB to perform its functions in bacterial DNA replication.[2] This interaction of DnaC with DnaB requires the hydrolysis of ATP.[3]
[edit] References
- ^ Fang, L, Davey, MJ, O'Donnell M (October 1999). "Replisome assembly at oriC, the replication origin of E. coli, reveals an explanation for initiation sites outside an origin". Mole. Cell. 4 (4): 541–53. doi:10.1016/S1097-2765(00)80205-1. PMID 10549286.
- ^ Wahle E, Lasken RS, Kornberg A (February 1989). "The dnaB-dnaC replication protein complex of Escherichia coli. II. Role of the complex in mobilizing dnaB functions". J. Biol. Chem. 264 (5): 2469–75. PMID 2536713. http://www.jbc.org/cgi/content/abstract/264/5/2469.
- ^ Kobori JA, Kornberg A (November 1982). "The Escherichia coli dnaC gene product. III. Properties of the dnaB-dnaC protein complex". J. Biol. Chem. 257 (22): 13770–5. PMID 6292205. http://www.jbc.org/cgi/content/abstract/257/22/13770.
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