In 1960, at age 15, she was invited to sing in a girl group called the Crystals. The group was formed by a band musician named Benny Wells who would soon become the group's manager. Wells was the uncle of Kenniebrew's bandmate Barbara Alston. Although she never sang lead on their songs (her voice was, according to her bandmate, Barbara Alston, "too high and soft"), she was the only member who stayed in the group from their formation to their disbanding. With the Crystals, she enjoyed a successful (but not very long) career in music. Their hits began to dry up after 1964 and they disbanded two years later.
In 1971, Kenniebrew and her former bandmates (Dolores "LaLa" Brooks, Mary Thomas, and Barbara Alston) reunited to tour and perform on the oldies circuit. However, in 1973, they disbanded again to devote their times to their families. Since the 1980s, she has kept the Crystals active in performing, but as a trio with two non-original members.