|Description||comprehensive collection of known and predicted domain-domain interactions.|
|Research center||National Institute of Environmental Health Sciences, National Institutes of Health|
|Primary citation||Yellaboina et al. (2011)|
DOMINE is a free and publicly available database of known and predicted protein domain interactions (or domain-domain interactions). It contains interactions observed in PDB crystal structures, and those predicted by several computational approaches. DOMINE uses Pfam HMM profiles for protein domain definitions. The DOMINE database contains 26,219 interactions among 5,410 domains), which includes 6,634 known interactions inferred from PDB structure data.
- Yellaboina et al. (Jan 2011). "DOMINE: a comprehensive collection of known and predicted domain-domain interactions". Nucleic Acids Res. (in eng) (England) 39 (Database issue): D730–5. doi:10.1093/nar/gkq1229. PMC 3013741. PMID 21113022.