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As with all white matter tracts, the DLF consists of myelinatedaxons carrying information between neurons. The DLF, carries both ascending and descending fibers, and conveys visceral motor and sensory signals.
Brainstem afferents in DLF include fibers coming from the parabrachial area, which conveys taste & general visceral sensation to the hypothalamus from the nucleus of the tractus solitarius in the medulla. Afferents distribute to the posterior nucleus and periventricular nuclei of the hypothalamus.