In the fetus, the ductus venosus shunts less than a third of the blood flow of the umbilical vein directly to the inferior vena cava. Thus, it allows oxygenated blood from the placenta to bypass the liver. In conjunction with the other fetal shunts, the foramen ovale and ductus arteriosus, it plays a critical role in preferentially shunting oxygenated blood to the fetal brain. It is a part of fetal circulation.
Postnatal closure 
The ductus venosus is open at the time of the birth and is the reason why umbilical vein catheterization works. Ductus venosus naturally closes during the first week of life in most full-term neonates; however, it may take much longer to close in pre-term neonates. Functional closure occurs within minutes of birth. Structural closure in term babies occurs within 3 to 7 days.
After it closes, the remnant is known as ligamentum venosum.
If the ductus venosus fails to occlude after birth, the individual is said to have an intrahepatic portosystemic shunt (PSS). This condition is hereditary in some dog breeds (e.g. Irish Wolfhound). The ductus venosus shows a delayed closure in preterm infants, with no significant correlation to the closure of the ductus arteriosus or the condition of the infant. Possibly, increased levels of dilating prostaglandins leads to a delayed occlusion of the vessel.
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